Medium-dose prednisolone pulse therapy in alopecia areata

comparison of oral prednisolone pulse therapy with intravenous methyl prednisolone pulse therapy in severe alopecia areata

High-dose pulse corticosteroid therapy: is it indicated for severe alopecia areata?

Accessible online at: www.karger.com/journals/drm In this issue of the journal, Seiter and his group report their experience with high-dose pulse corticosteroid therapy in the treatment of severe alopecia areata (AA) [1]. They treated 30 patients with intravenous methylprednisolone on 3 consecutive days at 4-week intervals for at least 3 courses; 67% of their patients with AA plurifocalis showe...

High-dose steroid pulse therapy for the treatment of severe alopecia areata.

Growing evidence shows alopecia areata (AA) to be a T cell-mediated organ-specific autoimmune disease. This study aimed to evaluate the efficacy of high-dose steroid pulse therapy in Taiwanese patients with severe widespread AA exceeding 40% of the scalp. A total of 17 Taiwanese patients with severe AA lasting less than 2 years were treated once monthly at the outpatient clinic for six sessions...

Low-Dose Systemic Methotrexate Therapy for Recalcitrant Alopecia Areata

BACKGROUND Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD-MTX) therapy in treatment of recalcitrant AA multiplex. METHODS In a retr...

Alopecia Areata Associated with Abacavir Therapy

Abacavir is a nucleoside reverse-transcriptase inhibitor that has been approved for use in combination with other retroviral agents in the treatment of HIV infection. Common adverse reactions include headache, fatigue, nausea, and rash. A fatal hypersensitivity reaction may occur in 5% of patients receiving abacavir; therefore, screening for HLA-B5701 should be performed before starting abacavi...